Molecular Diagnosis of Allergy: The Pediatric Perspective

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منابع مشابه

Contribution of molecular diagnosis of allergy to the management of pediatric patients with allergy to pollen.

BACKGROUND Component-resolved diagnosis based on recombinant allergens facilitates treatment of multiple sensitization and/or crossreactivity in allergic patients. OBJECTIVE To assess the usefulness of molecular diagnosis in childhood allergies. METHODS A total of 162 children aged 4-16 years diagnosed with allergic rhinitis or asthma/rhinitis caused by pollen were referred for recombinant ...

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Molecular diagnosis of egg allergy.

PURPOSE OF REVIEW Allergy to hen's egg is common in infancy and childhood. Oral food challenges are often required to diagnose egg allergy, because of the limitation in the diagnostic accuracy of skin test and specific IgE to egg white. New molecular diagnostic technologies have been recently introduced into allergological research. In this article, we will review the recent literature regardin...

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The Role of Anti-CCD Antibodies in Grape Allergy Diagnosis

Background: Allergens are mostly composed of glycoprotein structures. It is believed that glycan-specific antibodies may lead to false-positive reactions in immunoassays. In this study we investigated the glycosylation state of grape allergens as well as the presence of antibodies to cross-reactive carbohydrate determinants (anti-CCDs) in sera from grape-sensitive individuals. Methods: Grape...

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Molecular diagnosis of fruit and vegetable allergy.

PURPOSE OF REVIEW The purpose of this paper is to review and discuss studies on molecular diagnosis in fruit and vegetable allergy. RECENT FINDINGS Celeriac, carrot and tomato are the most prevalent allergenic vegetables, whereas fruit allergy is mainly induced by apple, peach and kiwi. Component-resolved molecular diagnosis has been recently applied in two well-defined patient groups with ki...

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ژورنال

عنوان ژورنال: Frontiers in Pediatrics

سال: 2019

ISSN: 2296-2360

DOI: 10.3389/fped.2019.00369